Dogs have nose for COVID-19, studies show. Why aren’t they used for testing?

As the availability of COVID-19 tests dwindle across Canada, another option to detect the virus in the form of a furry friend may be the next best thing.

Multiple studies show that dogs can be more effective, faster and potentially less expensive than the current tests on the market.

The research has grown since 2020, with University of California Santa Barbara professor Tommy Dickey finding the collective research shows trained scent dogs are “as effective and often more effective” than both the rapid antigen tests many people keep in their homes, and even the PCR tests deployed at clinics and hospitals.

But even with studies showing their effectiveness, COVID-19-detecting dogs are deployed only in certain jurisdictions in various countries.

One such place is the Canines for Care program at Vancouver Coastal Health (VCH), which started looking into the possibility of training dogs to detect COVID-19 in early 2021.

Dr. Marthe Charles, division head of medical microbiology and infection prevention and control at VCH, said the idea stemmed from the early reliance on laboratory testing.

“I think there was a will from public health at the time and also from the various levels of government to try to find a way that was fast, accurate and non-invasive to be able to detect and train as many people as possible,” Charles told Global News in an interview.

Three dogs — two Labrador retrievers and an English springer spaniel — were brought in for training. The dogs were exposed to items such as masks that were worn by patients either negative or positive for the virus. This trained the dogs to recognize what is and is not COVID-19.

Click to play video: 'Health Matters: COVID sniffing canine'

Charles said the dogs were trained since being puppies to associate the scent of COVID-19 with food and were rewarded each time they correctly detected a positive case of the virus.

“So from early on in their lives, they’ve associated the scent of a case of COVID to a rewarding scent,” she explained.

This reward method is not just used by VCM. It was also used with a group of dogs sourced in early 2021 for a French study, trained at detection using toys — usually tennis balls — as rewards.

Dr. Carla Simon, owner of Hunter’s Heart Scent Detection Canines in Calgary, said this method of training dogs is common. By using rewards, it can help motivate them to find the scent.

“We would pair, let’s say, the sweat samples with COVID, with their reward, and they notice that every time they find their reward, there’s that special smell,” she explained. “We just have to make it rewarding for the dog.”

She added, however, that the dog chooses the reward so trainers can ensure the canines “show up every day and want to do their job.”

Earlier this month, Dickey along with Heather Junqueira of BioScent, Inc. gathered several peer-reviewed studies into a review that was published in the Journal of Osteopathic Medicine. Dickey said the number of peer-reviewed studies over the past few years went from four to 29, incorporating the work of more than 400 scientists from more than 30 countries and 31,000 samples.

The review noted the effectiveness of dogs’ ability to detect COVID-19 comes down to their noses.

Click to play video: 'Study: Sniffer dogs can detect COVID-19 instantly'

“The nose is not like humans,” Simon said. “It’s massively different, orders of magnitude different, and they can detect things without us being able to smell them.” 

Humans have about five to six million olfactory receptors in their noses, while dogs have hundreds of millions. One-third of their brain is devoted to the interpretation of smell — something only five per cent of a human’s brain is committed to, according to Dickey’s review.

The study found dogs’ noses may even be able to detect pre-symptomatic COVID-19 cases, or even those who will develop symptoms later.

Dickey told us in an interview that this could help limit or stop the virus from spreading.

“The longer the wait is between your test and your result, that’s a latent period,” he said. “During that time you’re running around spreading COVID and you don’t know it. The dogs with a direct sniff will be done in seconds.”

Many of the studies conducted, including the work at VCH through the Canine for Care program, have shown dogs’ ability to detect the disease correctly with a success rate of more than 90 per cent. Additionally, the studies also showed a high speed at which the dogs could identify cases. In one study in  Thailand, researchers reported the dogs had gone through thousands of samples in just a few weeks.

“The dogs take only one to two seconds to detect the virus per sample. Once they detect a patient, they will sit down,” said Chulalongkorn University professor Kaywalee Chatdarong, who led the 2021 project.  “This takes only one to two seconds. Within one minute, they can manage to go through 60 samples.”

Even though the research suggested deploying scent-detection dogs could also be less expensive than rapid or PCR tests, Charles cautioned the logistics that go into training the dog is where it becomes “more prohibitive.”

Click to play video: 'Dogs trained to detect COVID-19 in Vancouver hospitals'

In VCH’s case, training of the dogs included the medical microbiology lab to provide samples for use, working with infection prevention teams and control nurses, and if a dog identifies an area of concern, cleaning services may need to be utilized. And when it comes to rolling out testing using the dogs, enough staffing is needed for mass screening.

Despite this, while Charles says deploying the dogs widely could be difficult due to staffing and training, they are still one of several tools that can be used in COVID-19 detection.

“I think the way to see those dogs from my perspective is really like another tool in the toolbox and trying to prevent further transmission of pathogen of concern,” she said.

Dickey and Junqueira say dogs should have a place in “serious diagnostic methodology” including in helping should the world face a future pandemic.

Can dogs really detect Covid-19 infections faster and more accurately than a lateral flow test?

Results indicated that not only can dogs detect Covid faster, but they can also do so in a non-intrusive manner – so no need to swab your throat or nose

Dogs can detect Covid-19 faster and more accurately than a PCR test, a new study shows.

Researchers looked at the ability of canines to recognise the virus and its variants, even when they are obscured by other viruses, like those from common colds and flu.

More than 400 scientists from over 30 countries contributed to the study as well as 147 scent dogs, according to the findings published in the Journal of Osteopathic Medicine.

After analysing many studies covering both field and clinical experiments, Professor Dickey and Junqueira found that dogs who are trained to sniff out scents are “as effective and often more effective” than antigen tests.

A total of 53 dogs were trained to sniff out Covid scents, while 37 were not and scientists found that the dogs that were not trained were in some cases “slightly superior” to those that were pre-trained.

“The previously untrained dogs have the advantage that they are not as prone to indicating on scents other than the Covid–19 associated scent,” the paper said.

The results indicated that not only can dogs detect Covid faster, but they can also do so in a non-intrusive manner. This means you won’t need to put a swab in your throat or nose.

How can dogs detect the virus?

This essentially comes down to the dog’s highly evolved nose with its ability to sense out smells quicker.

Dogs possess up to 300 million olfactory receptors in their noses, compared to about six million in humans. And the part of a dog’s brain that is devoted to analysing smells is about “40 times greater” than humans. Canines also have ‘neophilia’, which means they are attracted to new and interesting odours

And so, with all these enhancements, dogs can detect very low concentrations of odours associated with Covid infections.

“They can detect the equivalent of one drop of an odorous substance in 10.5 Olympic-sized swimming pools,” Professor Dickey said. “For perspective, this is about three orders of magnitude better than with scientific instrumentation.”

Scientists also found that in some cases, the animals were also able to detect the virus in pre-symptomatic and asymptomatic patients, “whose viral load was too low for conventional tests to work.”

Professor Dickey has said that dogs can also differentiate Covid and its different variants in the presence of other respiratory viruses. This included the common cold or flu.

“They’re much more effective. In fact, one of the authors that we quote in the paper commented that the RT-PCR test is not the gold standard anymore. It’s the dog. And they’re so quick,” he added. “They can give you the yes or no within seconds if they’re directly smelling you.”

How was the study conducted to see if dogs can really detect Covid-19?

In some studies, the dogs gave a person a quick sniff, sitting down to see if the person has Covid. In another study, the dog was given a sweat sample to smell for a few minutes.

The press release has said that scent dogs, such as beagles, basset hounds and coonhounds are the ideal candidates for sniffing out the virus, given their “natural tendencies to rely on odours to relate to the world.”

But the studies which the researchers analysed showed a variety of dogs were up for the challenge and were able to sniff out the Covid odour. With a few weeks of training, puppies, older dogs, purebred and mixed breeds, both male and female were able to sniff such odours out and “all performed admirably,” the Eureka Alert press release said.

Although there has been success with dogs detecting such viruses, researchers believe there are still many challenges with using dogs for medical diagnoses.

“There’s quite a bit of research, but it’s still considered by many as a kind of a curiosity,” said Professor Dickey.

In conclusion, Professor Dickey and Junqueira said after reviewing the studies, believe that scent dogs deserve “their place as a serious diagnostic methodology that could be particularly useful during future pandemics, potentially as part of rapid routine health screenings in public spaces.”

“Perhaps, most importantly, we argue that the impressive international quality and quantity of COVID scent dog research described in our paper for the first time, demonstrates that medical scent dogs are finally ready for a host of mainstream medical applications,” they added.

Related Posts

Be the first to comment

Leave a Reply

Your email address will not be published.


*